Fat Reduce cryo lipo is a minimally innovative technique to reduce waist fat, back fat and fat mass by selectively cooling subcutaneous fat. The technology was developed by Dr. R. Rox Anderson and his colleagues at Wellman Medical Center, Massachusetts General Hospital, Boston, USA. Zeltiq Aesthetics specializes in its commercial (equipment manufacturing and marketing) applications. The principle of Fat Reduce cryo lipo technology is that the energy absorption (cooling) equipment is applied to the skin surface to make the adipocytes crystallize above the freezing point of water, thereby destroying the adipocytes (apoptosis), and losing the peripheral nerves, blood vessels and skin surface tissue. According to the study of * related histology (pig and human), after 60 minutes (or shorter time) of frozen lipid treatment, there will be a low-grade inflammatory process lasting for 3 months: fat cells are phagocytosis by inflammatory cells and skin dermalfibrotic response. On the 90 day after treatment, the thickness of the subcutaneous fat layer of the treatment site decreased by 40%. Most of the participants had no (or mild) discomfort during treatment and after treatment. Therefore, no anesthesia is needed, and other activities such as Internet work can be undertaken at the same time.
ZELTIQ announced in late September 2015 that CoolMini, its freezing fat-dissolving facility, was approved by the FDA for the treatment of submental fat. CoolMini is specially designed for the treatment of small volumes of fat, such as submental fat, commonly known as "double chin," in terms of volume, shape and radian. Compared with traditional freezing fat dissolving equipment, CoolMini increases the efficacy and comfort of patients in small areas such as the chin and neck. According to ZELTIQ, the device appears to be effective as early as three weeks after treatment, and the best effect is usually achieved within one to three months of treatment. As a non-invasive fat-dissolving device, the comfort and satisfaction of patients treated with CoolMini have been greatly improved, with no downtime and no impact on daily life. According to the American Society of Dermatological Surgery (ASDS) in 2014, 68% of the population, more than 22 million people are very interested in the "non-invasive lipid" program. Ultrasound Fat Reduction Machine
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